Yildirim Cinar, A good. Mete Senyol, Kamber Duman, Blood viscosity and you may blood pressure level: part off temperature and you will hyperglycemia, American Record out-of Hypertension, Regularity fourteen, Procedure 5, , Users 433–438,
We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of gay hookup 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd. The purpose of our very own study should be to look into the relationships one of heat, sugar amount, and you may viscosity off blood and you can plasma, and to estimate its consequences towards the blood pressure levels (BP) predicated on Hagen-Poiseuille’s hydrodynamics picture. If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases. It’s been revealed that ranging from % and you can % viewpoints out of hematocrit, all the eleven% escalation in hematocrit grows bloodstream viscosity by the 20%. In this condition, predicated on Poiseuille’s equation, blood circulation speed reduces by the %, that may end in tissues ischemia. To store the fresh circulatory system within the equilibrium (which is, remaining the fresh disperse rate enough and you can preventing tissues ischemia), a great 20% increase in BP or cuatro.66% vasodilation required. step three not, the human being circulatory experience maybe not a precise signed program, because blood viscosity might be altered on the consumption from food otherwise pills. 4–8 Likewise, the results off fat as well as certain drugs on bloodstream viscosity and you will hemodynamics particularly BP was advertised. As the atherosclerotic vessels don’t dilate well enough just like the a reaction to vasodilator medicines, it’s been recommended one to improved bloodstream viscosity can only just end up being compensated having a great BP rise in such as products. 9–12 Along with, new dating one of BP, nightmare, coagulation, flow velocity, and bloodstream viscosity was basically demonstrated via the standards from hemodynamics. thirteen, 14Bloodstream viscosity and blood circulation pressure: part from temperatures and hyperglycemia