Population studies indicate that high intakes of calcium from the diet are linked with low BP, whereas clinical trials using calcium supplements to lower BP have been less compelling. 58, 59 A high dietary intake of calcium has been associated with both a decrease in BP and the risk of developing hypertension. In two studies, individuals receiving >800 mg/d of calcium compared with 400 mg/d achieved a 23% reduction in risk of developing hypertension. 60, 61 Ascherio and coworkers 23 also demonstrated in more than 30,000 normotensive male health professionals aged 40 to 75 years that men consuming <250 mg/d of calcium had a 50% greater chance of developing hypertension than those who consumed ?400 mg/d. Sacks and colleagues 52 reported no significant effect on BP in 94 patients randomly assigned to receive placebo or combination therapy with either calcium and magnesium or calcium and potassium for 6 months.
Calcium supplements supplements hasn’t been shown to end a boost in BP otherwise hypertension. On the Demonstration away from Blood pressure levels Protection (TOHP), 35 445 normotensive clients were randomly assigned to receive sometimes placebo otherwise step one grams away from calcium supplements everyday getting 6 months. There clearly was zero difference between BP between your groups. At the same time, TOHP-step one checked-out this new separate results of micronutrients with the BP in the hypertensive customers that have a beneficial diastolic BP away from 80 so you’re able to 89 mm Hg. Expands when you look at the slimming down calcium supplements and magnesium got merely a small impression on the BP, whereas restriction of sodium consumption and you can losing weight led to extreme reduces during the BP. 35
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